What Is The Harmful of Nicotine？

What Is The Harmful of Nicotine? Nicotine, the main active ingredient in e-cigarette products, is addictive, so are there any other dangers that we can explore in this article.

Introduction

Nicotine  is a naturally occurring alkaloid in plants of the Solanaceae family, which has become the core addictive substance in tobacco products since it was industrially extracted in the 19th century. Although nicotine itself is not a direct carcinogen, it is an addictive substance that indirectly causes smokers to jeopardize their bodies by long-term absorption of thousands of toxic compounds produced when tobacco is burned. According to the World Health Organization (WHO), nicotine dependence is considered a key factor in maintaining smoking behavior.

The Pharmacokinetics of Nicotine

When nicotine enters the body, it will be transmitted through the bloodstream, and it takes only 7 seconds on average to reach the brain after inhalation, and the half-life of nicotine in the human body is about 2 hours.

The liver is the main organ that metabolizes nicotine. Nicotine binds to nicotinic acetylcholine receptors and strengthens acetylcholine, thus equating to an increase in the amount of neurotransmitters, which increases the amount of dopamine secreted by the brain and produces a sense of well-being and relaxation, which is the reason for the absorption of nicotine addiction.Nicotine also stimulates the visceral nerves, releasing more adrenaline.

The Harm of Nicotine

Because nicotine can release adrenaline by stimulating the sympathetic nerves, leading to faster heart rate, higher blood pressure and vasoconstriction. A moderate amount of nicotine is what the body can tolerate, but long-term excessive nicotine intake can lead to long-term load on the heart and blood vessels, so it is recommended to use in moderation.

Excessive nicotine intake can lead to nicotine toxicity producing symptoms such as nausea, vomiting, abdominal pain, headache, and rapid heartbeat, at which point it is necessary to stop nicotine intake, drink plenty of water, and wait for the liver to metabolize the excessive amount of nicotine in the body.

The nicotine in electronic cigarettes

E-cigarettes are less harmful than burning tobacco, nicotine in e-cigarettes and tobacco are the same harm, long-term intake are addictive, but e-cigarettes are produced by atomizing e-cigarette liquid smoke, intake of ingredients for the components of the e-cigarette liquid, while the smoke produced by tobacco is produced by igniting the smoke produced by tobacco, which contains thousands of be burned to produce toxic substances.