{"id":1,"date":"2025-03-13T14:17:53","date_gmt":"2025-03-13T14:17:53","guid":{"rendered":"http:\/\/49.233.50.253\/?p=1"},"modified":"2025-04-14T10:15:04","modified_gmt":"2025-04-14T10:15:04","slug":"what-is-the-harmful-of-nicotine","status":"publish","type":"post","link":"https:\/\/vapesaler.com\/cs\/what-is-the-harmful-of-nicotine.html","title":{"rendered":"Jak \u0161kodliv\u00fd je nikotin\uff1f"},"content":{"rendered":"

Jak \u0161kodliv\u00fd je nikotin? Nikotin, hlavn\u00ed \u00fa\u010dinn\u00e1 slo\u017eka v\u00fdrobk\u016f elektronick\u00fdch cigaret, je n\u00e1vykov\u00fd, existuj\u00ed tedy n\u011bjak\u00e1 dal\u0161\u00ed nebezpe\u010d\u00ed, kter\u00e1 m\u016f\u017eeme v tomto \u010dl\u00e1nku prozkoumat.<\/p>\n

\u00davod<\/h2>\n

Nikotin je p\u0159irozen\u011b se vyskytuj\u00edc\u00ed alkaloid v rostlin\u00e1ch z \u010deledi Solanaceae, kter\u00fd se stal hlavn\u00ed n\u00e1vykovou l\u00e1tkou tab\u00e1kov\u00fdch v\u00fdrobk\u016f od doby, kdy byl v 19. stolet\u00ed pr\u016fmyslov\u011b z\u00edsk\u00e1v\u00e1n. P\u0159esto\u017ee nikotin s\u00e1m o sob\u011b nen\u00ed p\u0159\u00edm\u00fdm karcinogenem, jedn\u00e1 se o n\u00e1vykovou l\u00e1tku, kter\u00e1 nep\u0159\u00edmo zp\u016fsobuje, \u017ee ku\u0159\u00e1ci ohro\u017euj\u00ed sv\u016fj organismus dlouhodob\u00fdm vst\u0159eb\u00e1v\u00e1n\u00edm tis\u00edc\u016f toxick\u00fdch slou\u010denin vznikaj\u00edc\u00edch p\u0159i spalov\u00e1n\u00ed tab\u00e1ku. Podle Sv\u011btov\u00e9 zdravotnick\u00e9 organizace (WHO) je z\u00e1vislost na nikotinu pova\u017eov\u00e1na za kl\u00ed\u010dov\u00fd faktor udr\u017eov\u00e1n\u00ed ku\u0159\u00e1ck\u00e9ho chov\u00e1n\u00ed.<\/p>\n

Farmakokinetika nikotinu<\/h2>\n

Nikotin se do t\u011bla dost\u00e1v\u00e1 krevn\u00edm \u0159e\u010di\u0161t\u011bm a do mozku se po vdechnut\u00ed dostane v pr\u016fm\u011bru za pouh\u00fdch 7 sekund, p\u0159i\u010dem\u017e polo\u010das rozpadu nikotinu v lidsk\u00e9m t\u011ble je p\u0159ibli\u017en\u011b 2 hodiny.<\/p>\n

J\u00e1tra jsou hlavn\u00edm org\u00e1nem, kter\u00fd metabolizuje nikotin. Nikotin se v\u00e1\u017ee na nikotinov\u00e9 acetylcholinov\u00e9 receptory a posiluje acetylcholin, co\u017e se rovn\u00e1 zv\u00fd\u0161en\u00ed mno\u017estv\u00ed neurotransmiter\u016f, kter\u00e9 zvy\u0161uj\u00ed mno\u017estv\u00ed dopaminu vylu\u010dovan\u00e9ho mozkem a vyvol\u00e1vaj\u00ed pocit pohody a uvoln\u011bn\u00ed, co\u017e je d\u016fvodem vst\u0159eb\u00e1v\u00e1n\u00ed z\u00e1vislosti na nikotinu. nikotin tak\u00e9 stimuluje viscer\u00e1ln\u00ed nervy a uvol\u0148uje v\u00edce adrenalinu.<\/p>\n

\u0160kodlivost nikotinu<\/h2>\n

Nikotin toti\u017e m\u016f\u017ee uvol\u0148ovat adrenalin stimulac\u00ed sympatick\u00fdch nerv\u016f, co\u017e vede ke zrychlen\u00ed srde\u010dn\u00ed frekvence, zv\u00fd\u0161en\u00ed krevn\u00edho tlaku a z\u00fa\u017een\u00ed c\u00e9v. M\u00edrn\u00e9 mno\u017estv\u00ed nikotinu t\u011blo snese, ale dlouhodob\u00fd nadm\u011brn\u00fd p\u0159\u00edjem nikotinu m\u016f\u017ee v\u00e9st k dlouhodob\u00e9mu zat\u00ed\u017een\u00ed srdce a c\u00e9v, proto se doporu\u010duje u\u017e\u00edvat ho s m\u00edrou.<\/p>\n

Nadm\u011brn\u00fd p\u0159\u00edjem nikotinu m\u016f\u017ee v\u00e9st k nikotinov\u00e9 toxicit\u011b, kter\u00e1 se projevuje nevolnost\u00ed, zvracen\u00edm, bolestmi b\u0159icha, bolestmi hlavy a zrychlen\u00fdm srde\u010dn\u00edm tepem.V takov\u00e9m p\u0159\u00edpad\u011b je nutn\u00e9 ukon\u010dit p\u0159\u00edjem nikotinu, p\u00edt hodn\u011b vody a po\u010dkat, a\u017e j\u00e1tra metabolizuj\u00ed nadm\u011brn\u00e9 mno\u017estv\u00ed nikotinu v t\u011ble.<\/p>\n

\"Nikotinov\u00e1<\/p>\n

Nikotin v elektronick\u00fdch cigaret\u00e1ch<\/h2>\n

E-cigarety jsou m\u00e9n\u011b \u0161kodliv\u00e9 ne\u017e spalov\u00e1n\u00ed tab\u00e1ku, nikotin v e-cigaret\u00e1ch a tab\u00e1k jsou stejn\u00e9 \u0161kody, dlouhodob\u00fd p\u0159\u00edjem jsou n\u00e1vykov\u00e9, ale e-cigarety jsou vyr\u00e1b\u011bny rozpra\u0161ov\u00e1n\u00edm e-cigarety kapaln\u00fd kou\u0159, p\u0159\u00edjem slo\u017eek pro slo\u017eky e-cigarety kapaliny, zat\u00edmco kou\u0159 produkovan\u00fd tab\u00e1kem se vyr\u00e1b\u00ed zap\u00e1len\u00edm kou\u0159e produkovan\u00e9ho tab\u00e1kem, kter\u00fd obsahuje tis\u00edce b\u00fdt sp\u00e1len za vzniku toxick\u00fdch l\u00e1tek.<\/p>","protected":false},"excerpt":{"rendered":"

Jak \u0161kodliv\u00fd je nikotin? Nikotin, hlavn\u00ed \u00fa\u010dinn\u00e1 slo\u017eka v\u00fdrobk\u016f elektronick\u00fdch cigaret, je n\u00e1vykov\u00fd, existuj\u00ed tedy n\u011bjak\u00e1 dal\u0161\u00ed nebezpe\u010d\u00ed, kter\u00e1 m\u016f\u017eeme prozkoumat?<\/p>","protected":false},"author":2,"featured_media":899,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"footnotes":""},"categories":[144],"tags":[],"class_list":["post-1","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/vapesaler.com\/cs\/wp-json\/wp\/v2\/posts\/1","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vapesaler.com\/cs\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vapesaler.com\/cs\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vapesaler.com\/cs\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/vapesaler.com\/cs\/wp-json\/wp\/v2\/comments?post=1"}],"version-history":[{"count":0,"href":"https:\/\/vapesaler.com\/cs\/wp-json\/wp\/v2\/posts\/1\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/vapesaler.com\/cs\/wp-json\/wp\/v2\/media\/899"}],"wp:attachment":[{"href":"https:\/\/vapesaler.com\/cs\/wp-json\/wp\/v2\/media?parent=1"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vapesaler.com\/cs\/wp-json\/wp\/v2\/categories?post=1"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vapesaler.com\/cs\/wp-json\/wp\/v2\/tags?post=1"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}